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Topics:
Rheumatology • Myositis • Sjogren’s syndrome • Neurology • Neuromuscular • Inclusion body myositis
Do you consider immunosuppression in patients with a history of Sjogren's disease and clinical features of inclusion body myositis?
Patient with long-standing history of Sjogren's (+SSA) and muscle weakness (muscle biopsy showed chronic myopathic changes with Lymphocytic inflammation and femur MRI with fatty infiltration of quadriceps and vastus lateralis muscles), CK normal at 160 U/L.
Answer from: at Academic Institution
My short answer is no. The phenotype and MRI findings described in this case suggest IBM and recently published consensus criteria for the diagnosis of IBM require only the presence of endomysial lymphocytic inflammation in muscle biopsy as a mandatory criterion, along with supportive clinical pheno...
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