Do you counsel patients to take antihypertensives at specific times of day to maximize efficacy or minimize side effects?

I counsel my patients to take antihypertensives in the morning. The only exception is the alpha-1 antihypertensives. I use them only as an add-on, to be taken at bedtime for two reasons: one is to avoid the blood pressure surge in the early morning hours, and two is to minimize orthostatic blood pre...

Generally, I emphasize medication adherence over the time of day. As long as it is a once-a-day medication and they are not having other side effects, I tell them that the best time to take their medication is the time that they will always remember.