I do consider a shorter course of ADT in the setting of a patient with significant cardiac disease, but usually only after speaking with the patient's cardiologist to first determine if there may be other mitigating risk factors that are more readily modifiable. If the patient is olde...

The increased risk of cardiovascular mortality after androgen ablation data is mixed. In a pooled analysis of randomized trials in unfavorable-risk prostate cancer published in JAMA, ADT use was not associated with an increased risk of cardiovascular death but was associated with a lower risk of PCS...

Agree with all of @Sushil Beriwal's points. In the end, you often have to gauge the right thing to do based on the patient in front of you as much as on the literature. The truth of the matter is that I am often far more concerned about impacting negatively on bone mineral density (BMD) than cardiac...