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Do you ever alter dose/fractionation for early stage endometrial cancer patients receiving vaginal brachytherapy alone?

And if so, in which situations do you offer differing doses?
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What is your preferred vaginal cylinder HDR brachytherapy prescription for women with early stage endometrial cancer?

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1 Answer
Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · University of Kentucky
Answered on

There are several commonly used regimens for vaginal brachytherapy alone. In GOG 249, the following regimens were allowed:

  1. HDR 6-7 Gy x 3 fractions, weekly, prescribed at a depth of 0.5 cm from the surface of the vagina.
  2. HDR 10-10.5 Gy, x 3 fractions, weekly, prescribed at the vaginal surface.
  3. HDR 6 Gy...

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