Do you ever check antibodies against EBV as part of a workup for MS in a patient with white matter lesions of unclear etiology on MRI?

Generally, we do not check for antibodies against either viral capsid antigen (VCA) or Epstein Barr nuclear antigen (EBNA) for our patients with MS or when MS.

EBV is considered a common infection. A large portion of the adult population, 90-95%, is seropositive for EBNA antibodies (Lincoln et al., P...