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Do you ever delay starting levodopa in patients with Parkinson's disease?

In light of the long-term follow-up of the LEAP study published in 2024 - Frequin et al., PMID 38644623
1 Answer
Mednet Member
Mednet MemberInvited Expert
Neurology · University of Miami Miller School of Medicine
Answered on

With LEAP and the 5-year follow-up study, we can feel comfortable deciding to start patients early on levodopa to maximize quality of life via motor symptom control.

In this study, there were no differences in UPDRS scores, the prevalence of wearing off, or levodopa equivalent daily dose between the...

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