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Do you ever treat patients with phyllodes tumor of the breast with adjuvant radiation?

Do your post-operative treatment recommendations differ for benign vs. malignant phyllodes tumors of the breast? Is phyllodes tumor size ever a criterion for post-operative radiation?
2 Answers
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Radiation Oncology · Beth Israel Deaconess Medical Center
Answered on

The risk of local recurrence is small for patients with benign phyllodes tumors treated with lumpectomy or mastectomy, even if there are positive margins. Recurrences are almost always benign. Hence, there is no role for adjuvant RT for such patients. The available literature does not allow one to d...

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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on · Updated on

There is no good consensus and published guidelines are also not consistent.

Sars et al., PMID 36879102

I usually limit RT for borderline and malignant phyllodes after breast-conserving surgery for tumors 4 cm or larger, close margin (and no re-excision possible), or recurrent disease.

After mastecto...

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