Do you have a preference between an ACEi and ARB when initiating therapy for a patient with diabetic kidney disease, albuminuria, and hypertension?  

Why would you use an ACEi over an ARB these days? Cough is a LOT more common than stated. I see patients all the time who have a ticket, an annoyance that goes away on an ARB. Also, I don't see a $ argument, nor am I aware that ACEi have even been shown to be superior to ARB for reno protection.&nbs...

In short, no. There are outcome data supporting both ACE inhibitors and ARBs (though not together) in slowing the progression of CKD in DM nephropathy. I typically consider allergy profiles, comorbidities like respiratory disorders, and availability of combination therapies when choosing to start an...

Assuming we are talking about type 2 diabetic patients, I prefer ARBs, as they generally have a safer side effect profile. They are also more potent as anti-hypertensive agents. 

If you are going to use losartan as a hypertensive, it needs to be given twice a day as the duration of action is 12 hours.

I agree that ACE inhibitors are associated with more side effects compared to ARBs; however, Cheng et al., PMID 24687000 demonstrated superior cardiovascular benefits and reduced all-cause mortality in diabetic patients treated with ACE inhibitors (not a head-to-head trial; this is just a meta-analy...