Do you hold osimertinib when delivering partial or whole brain 3D radiation?
If so, how many days before and after? Does this change if delivering SRS?
Answer from: Radiation Oncologist at Academic Institution
I typically don't mandate holding osimertinib while administering SRS for brain metastases unless my medical or neuro-oncologist has concerns. In such cases, I might consider delaying the initiation of osimertinib for about a week. Notably, there are two prospective studies (NCT03769103 and NCT03497...
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