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Do you include bevacizumab with chemotherapy in patients with metastatic colon cancer with an intact primary tumor who have intermittent obstructive symptoms?

How do you assess the risk of complications from including bevacizumab vs the known benefits of including it with chemotherapy?
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What would you recommend for a patient with newly diagnosed metastatic sigmoid colon CA with synchronous liver mets and near obstruction on CT?

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1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · Duke University
Answered on

I agree with Dr. @Dr. First Last. If I am worried that obstruction could happen but we are not at the point where we need to pause for a diversion, I will start chemo without bevacizumab for the first 2 to 3 doses - so that we get that response that he mentions - and then I can add without being too...

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