Do you incorporate the ALASCCA trial into your clinical practice and perform NGS on all early stage colon cancer patients to determine if adjuvant aspirin would be beneficial?
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Which patients with Stage II/III colon cancer will you offer adjuvant aspirin 162 mg daily per ALASCCA?
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1 Answer
Mednet MemberInvited Expert
Medical Oncology · Lurie Comp Cancer Center of Northwestern Univ
Answered on
Yes, I recommend obtaining PIK3CA testing on patients with resectable colon and rectal cancer based on the ALASCCA trial, as well as other data for patients who are able to receive low-dose aspirin if they have a PIK3CA mutation. NCCN guidelines currently recommend post-surgery/adjuvant therapy aspi...
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