Mednet Logo
CommunityNephrology

Do you interpret failure to develop hypernatremia with prolonged water deprivation (such as for 12 hours) as evidence against diabetes insipidus even if the urine osmolality is just below normal?

For a patient whose sodium remains 142 despite water deprivation from 8 pm to 8 am, with urine osm of about 500, is further testing needed?
Community PollStarted

How do you interpret failure to develop hypernatremia with prolonged water deprivation (such as for 12 hours) and a urine osmolality just below normal?

47 physicians have voted

Join Mednetto vote and see how they answered.

2 Answers
Mednet Member
Mednet MemberInvited Expert
Endocrinology · University of Alabama at Birmingham
Answered on

This test indicates that this patient has fairly good urinary concentrating ability, but does not meet most criteria for "normal" since the osmoles did not go over 600. Since diabetes insipidus is a spectrum disorder, this result does not completely rule out the possibility of very mild diabetes ins...

Join for free or sign in to see the full answer

Mednet Member
Mednet MemberInvited Expert
Endocrinology · Kaiser Permanente Oakland Medical Center Endocrinology
Answered on

Agree

Join for free or sign in to see the full answer