Do you offer adjuvant radiation therapy for sacral chordoma s/p gross total resection with close margins <0.5 cm?
What dose would you use? For negative margins do you offer 50-50.4 Gy/25-28 fractions? What target volume margins do you typically recommend on the post-operative bed?
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · The Ohio State University - James Cancer Hospital and Solove Research Institute
Answered on
Yes to adjuvant RT, but doses of 50-60 Gy have no benefit in chordoma. 70 Gy is required even with R0 margins. See Konieczkowski et al., PMID 32147017 for a full discussion of the literature.
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