Do you offer hypofractionated accelerated whole breast radiation therapy for women receiving trastuzumab during RT, particularly those with left sided primaries?
In START B ~ 23 % of women received some form of cytotoxic chemotherapy, and the trial was conducted in the trastuzumab era, but there is no mention of trastuzumab specifically in the publication. Is there any other available data to help guide us in this?
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Do you offer hypofractionated WBI for women receiving trastuzumab during RT?
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Radiation Oncology · Varian Medical Systems/Allegheny health network
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In the modern era for breast RT the radiation field should not be transversing through heart (a conformal block, the prone position or DIBH technique can help prevent radiation to the heart) and with one of these techniques mean heart dose is 1 to 2 Gy (most of this dose comes from scatter or transm...
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Radiation Oncology · Rutgers Robert Wood Johnson Medical School
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The new ASTRO guideline on whole breast fractionation recently published in Practical Radiation Oncology (PRO) concluded that the decision to offer hypofractionation should be independent of breast laterality and independent of chemotherapy received prior to radiation or trastuzumab or endocrine the...
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