Do you offer iron supplementation to a patient with iron studies that are normal (including normal ferritin) except for low iron saturation?

The answer is absolutely and positively yes. A low percent saturation of transferrin has an extremely high concordance with absent marrow hemosiderin and frankly, in today’s parlance is the best indicator of “iron need”. While the ferritin is marvelous at confirming iron deficiency if low (with or w...