Do you offer IVIG to myeloma patients with recurrent infections?

I do offer IVIG to patients with myeloma who are having recurrent respiratory infections and have hypogammaglobulinemia (<400 mg/dL). I do counsel patients that we do not have strong clinical trial data to support the use of IVIG in this setting. While I dislike quoting anecdotal experience, I will say that I do think this practice decreases the rate and severity of infections.

The available literature would suggest otherwise though, at least in retrospective studies (e.g., Park et al., PMID 2620...