Do you offer PCI for resected mixed histology lung cancers with a minor component of small cell?

Most mixed histology small cell and many resected cases are from removal of solitary pulmonary nodules.

If there is foreknowledge of a small-cell component, more attention to N1 and N2 stations is warranted. If nodes are clear, chemotherapy remains warranted but likely thoracic radiotherapy (TRT) is not. From the CREST trial in ED SCLC probing value of TRT in improving 1 and 2 year survival, little benefit was found in patients have a CR to chemotherapy.

Observational studies of resected small c...