Do you order MODY genetic testing to discontinue unnecessary treatments such as insulin or metformin in patients misdiagnosed as either Type 1 diabetes or Type 2 diabetes?

First, I like the term Monogenic Diabetes better than MODY because it captures the concept of a single-gene mutation to distinguish it from the multi-gene/environmental factors in T1DM and T2DM. I think screening for monogenic diabetes should be considered in patients with atypical features of T1DM or T2DM to assist with directing therapy as well as to help with genetic counseling for patients interested in having children. Criteria to consider testing include early-onset diabetes that is antibody negative, multigenerational history of diabetes, stable fasting hyperglycemia, and T2DM in a young adult who is non-obese (Guidelines for Genetic Testing in MODY). However, screening criteria could be broadened in cases where the provider is conce...