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Do you perform PDL1 and molecular testing for patients with stages I-III NSCLC?

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Do you order PDL1 and molecular testing for patients with stages I-III NSCLC?

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6 Answers
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Medical Oncology · University of Virginia
Answered on · Updated on

Do you order PDL1 and molecular testing for patients with stages I-III NSCLC?

When I answered this question about two years ago, I said no, primarily because there was no Level 1 efficacy data to support an improvement in outcomes for these patients. This has since changed... although in some ways, n...

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Medical Oncology · Fox Chase Cancer Center
Answered on
Stage III patients are at a higher risk of recurrence. I consider these patients an "at risk" population and I'd like to have the molecular data and the PD-L1 status determined at the time of diagnosis. Of course, I am talking about stage III patients eligible for tri modality treatment. If they are...

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Medical Oncology · University of Virginia
Answered on

At our site, we perform both PDL1 and molecular testing internally. For the last several years, our thoracic group has had a reflex testing agreement in place with our pathologists to initiate both PDL1 and molecular testing for all patients when pathology is consistent with non-squamous NSCLC, incl...

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Medical Oncology · University of Illinois College of Medicine at Chicago
Answered on

We perform next generation sequencing and PD-L1 testing on all lung cancer patients regardless of stage or histology.

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Medical Oncology · Gerard J Ventura MD, FACP
Answered on · Updated on

I do because with some Stage III individuals expressing 50% PD-L1 we can use Keytruda monotherapy if they are ineligible for standard combined modality therapy. I currently test the 'actionable' (ie, treatable) mutations as per NCCN. I'm curious how many people instead routinely order the 50-100+ sh...

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Thoracic Surgery · University of Michigan Medical School
Answered on

For patients who are post operative and are candidates for adjuvant therapy, we will perform PD-L1 testing.

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