Do you perform routine interval screening for pulmonary fibrosis in individuals who have been identified through genetic testing as being at risk for developing pulmonary fibrosis but don't exhibit any signs or symptoms?
Specifically considering individuals with known mutations in MUC5B, TERT/TERC, etc
2 Answers
Mednet MemberInvited Expert
Pulmonology · University of Colorado School of Medicine
Answered on
Screening for pulmonary fibrosis:
- Only "yes" for individuals with one or more family members with IPF and age >50 - HRCT findings of ILAs, fibrotic ILAs, or IPF will be identified in 20% of these individuals.
- No for all other individuals including those carrying various high-risk alleles such as M...
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Mednet MemberInvited Expert
Pulmonology · Strong Memorial Hospital
Answered on
I would start by questioning why an individual would have genetic testing for ILD without a strong family history or as a participant in a research study (i.e. be identified as having a genetic mutation in MUC5B or TERT/TERC).
Secondly, the type of screening needs to be defined. The Gold standard for...
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