Do you prescribe a low-dose tricyclic antidepressant as a gut-brain neuromodulator for a patient with IBS that has not responded to dietary modification and first-line pharmacotherapy?
1 Answer
Mednet MemberInvited Expert
Gastroenterology · Icahn School of Medicine at Mount Sinai
Answered on
Yes, I do. In fact, I consider a tricyclic like imipramine (highest GI effects) to be first-line pharmacotherapy.
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