Have you used oral carbapenems to treat an outpatient with a complicated UTI caused by an ESBL-producing organism who would otherwise require hospitalization for IV carbapenem therapy, given concerns about community carbapenem stewardship?

To date, the only oral carbapenem that is licensed in the U.S. is tebipenem. I have no experience with this drug and would be very interested in using it when it becomes readily available.

I have not used an oral carbepenem to treat an ESBL UTI at present. At this point, they are not used frequently, and generally when patients have a complicated UTI to the point that they are sick enough that they require a carbepenem they may need hospitalization for other reasons. Moreover, the oral cabapenems are not readily available for my patients due to financial reasons, formularies, etc. As such, I have not prescribed them. However, if it does allow for prevention of hospitalization, I w...