Do you proactively convert stable kidney transplant recipients from twice-daily immediate release tacrolimus to once-daily extended release tacrolimus to improve long-term adherence?

What is your approach to converting stable kidney transplant recipients from twice-daily immediate release tacrolimus to once-daily extended release tacrolimus?

• I proactively convert stable patients to once-daily tacrolimus to improve long-term adherence
• I convert selectively based on individual patient factors such as adherence history or side effect profile
• I convert only when a patient requests it or reports difficulty with the twice-daily regimen
• I do not routinely convert stable patients given concerns about bioavailability differences and the risk of destabilizing a stable regimen
• I would convert but insurance coverage and cost are prohibitive barriers in my practice
• Other