Do you recommend a particular antiresorptive/anabolic agent for patients who are at high risk for fractures but have high risk of osteonecrosis of the jaw?
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Which antiresorptive/anabolic agent do you recommend for patients who are at high risk for fractures but also have a high risk of osteonecrosis of the jaw?
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3 Answers
Mednet MemberInvited Expert
Endocrinology · University of Missouri School of Medicine
Answered on
Teriparatide has improved bone healing in patients with osteonecrosis of the jaw, so would be a good choice for patients at high risk of ONJ.
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Mednet Member
Rheumatology · UCLA
Answered on
PTH analogues are the only osteoporotic medications that do not have the risk of ONJ. Romosozumab has antiresorptive features and has been reported to cause ONJ.
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Mednet MemberInvited Expert
Endocrinology · Providence John Wayne Cancer Institute Endocrinology
Answered on
Either would be effective but there would be greater risk with Prolix.
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