Do you recommend a prolonged duration of antibiotics and/or suppression for patients without pre-existing hardware who have placement of new hardware after decompression/washout of staph aureus epidural abscess?   

This can be a difficult clinical scenario and the answer depends in part on whether there was any concern for osteomyelitis at the time the epidural abscess was drained. If so, I would suggest giving a prolonged duration of abx with 6 weeks of targeted IV abx therapy and oral Rifampin followed by 3 ...