Do you recommend adjuvant chemotherapy to a low risk T3N0 stage II colon cancer if there was bowel perforation upstream from the tumor, with mucosa underlying tumor itself being intact?

The upstream perforation is likely from another cause like inflammatory bowel disease, I am assuming. In this situation, I would offer chemo regardless of the upstream perforation. I would consider if they are eligible for a clinical trial that is incorporating ctDNA to help decide. But my understan...