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Do you recommend adjuvant or indefinite systemic therapy after surgery/radiation for patients with synchronous bilateral breast cancers that are of the same histology and receptor status?

Given the poorer prognosis of these patients, do you approach their treatment any differently than a unilateral cancer?
1 Answer
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Medical Oncology · Cleveland Clinic Florida
Answered on

Synchronous bilateral breast cancer is rare and often presents with concordant histology, but is generally considered 2 primaries rather than metastatic disease due, possibly, to common exposures of similar clones. Despite controversy and conflicting reports, long term survival has been reported. It...

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