Do you recommend adjuvant radiotherapy for an adult patient with localized myxopapillary ependymoma, WHO Grade 2, status-post gross total resection?
Answer from: Radiation Oncologist at Academic Institution
I assumed that this is a case of spinal ependymoma. Myxopapillary ependymomas are rare tumors and optimal therapeutic strategy involves a Gross Total Resection (GTR). The more complete the surgery the better the outcome. The role of postoperative radiation after a GTR is somewhat controversial but I...
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Answer from: Radiation Oncologist at Academic Institution
Before the 2021 WHO Classification of CNS Tumors was released, spinal myxopapillary ependymoma (MPE) was classified as grade 1 as it was commonly recognized as a slow-growing and fairly indolent neoplasm. However, in 2021, it was reclassified as grade 2. This change was prompted by an evolving under...