Do you recommend GLP-1 agonists in patients with MPN?

I don't think that there is a compelling reason to start a GLP-1 agonist without another indication. With that said, there was a provocative recent abstract at SOHO suggesting a significant reduction in mortality, thrombosis, and disease progression in GLP-1-treated PV patients compared to those who...

I agree with Dr. @Dr. First Last, although the data presented at SOHO were very provocative, demonstrating benefits to GLP-1 agonists in MPN patients, we do not currently have any prospective data or consensus guidelines to recommend the use of these agents for MPN alone.

That being said, anecdotal...