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Topics:
Infectious Disease • Neurology • Neuro-infectious disease • General Infectious Disease • Neurohospitalist
Do you recommend immunomodulating treatments such as steroids or IVIG for West Nile Virus neuroinvasive disease?
Answer from: at Academic Institution
In review of the literature and CDC recommendations, the outcomes when using IVIG in this setting are variable. It has been utilized in immunocompromised patients such as solid organ transplant recipients. I have not found enough evidence to support using it in a non-immunocompromised patient. The s...
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Answer from: at Community Practice
The concept for using ivIG is for passive immunity.
There is expected to be a huge variation in the pooled ivIG from the population-based donors.
Not all antibodies are necessarily protective.
Antibody from the donated blood varies based on the seasonality and region of donors and the circulati...