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Do you recommend IV sodium bicarbonate for patients with rhabdomyolysis and AKI without metabolic alkalosis or hypocalcemia?

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What is your preferred IV fluid for patients with rhabdomyolysis and AKI without metabolic alkalosis or hypocalcemia?

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4 Answers
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Nephrology · The University of Texas Health Science Center at San Antonio
Answered on

The primary goal of IV fluids and urine alkalinization in patients with rhabdomyolysis is to prevent AKI, not to treat established AKI. The most important factor in preventing AKI is early and vigorous fluid administration (aiming to achieve a brisk diuresis of 200-400 ml/hr), while the choice of IV...

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Nephrology · Saint Lukes Nephrology Associates Of Carbon County
Answered on

The most important strategy is to induce a diuresis to prevent ATN.

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Nephrology · Harvard Medical School
Answered on

Give generous IV saline for this toxic type ATN

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Nephrology · UCLA
Answered on

No. There is no clear clinical evidence demonstrating that an alkaline diuresis is more effective than a saline diuresis in the prevention and treatment of AKI in the setting of rhabdomyolysis, given the lack of a direct comparative trial. Therefore, aggressive saline hydration is typically recommen...

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