Do you recommend low or intermediate dosing of TMP-SMX over high dosing for the initial treatment of non-disseminated pulmonary nocardiosis?

I would use low or intermediate dosing for non-disseminated pulmonary nocardiosis. I am not familiar with evidence supporting high-dose in this setting, and a retrospective review from investigators from the Mayo clinic sites last year showed similar outcomes (Yetmar et al., PMID 38922564). High-dos...