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Do you recommend lumbar puncture for suspected early GBS without motor involvement?

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Do you recommend lumbar puncture for suspected early GBS without motor involvement?

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1 Answer
Mednet Member
Mednet MemberInvited Expert
Neurology · University of Maryland School of Medicine
Answered on

If purely for the confirmation of a GBS diagnosis, then no.

CSF testing has limited utility for Guillain-Barré syndrome (GBS) diagnosis early in the disease course. Cytoalbuminologic dissociation is only present in 50% of patients in the first four days and rises to ~80% after the first week (Al-Hake...

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