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Do you recommend menstrual suppression for post-menarchal adolescents and young adults receiving myelosuppressive chemotherapy?

If yes, by what mechanism?
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Do you recommend menstrual suppression for post-menarchal AYA patients receiving myelosuppressive chemotherapy?

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2 Answers
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Pediatric Hematology/Oncology · UCSF
Answered on

One other point of consideration is the potential benefit of GnRH agonists (i.e., Lupron) on the reproductive potential of post-pubertal females given the risk of chemotherapy in decreasing years of fertility (i.e., earlier menopause). Though data on GnRH agonists is limited to females with breast c...

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Mednet Member
Mednet MemberInvited Expert
Pediatric Hematology/Oncology · Children’s National Hospital
Answered on

I do not routinely intentionally suppress menses in post pubertal females unless an issue arises - and that issue is usually that the patient feels that they are bleeding more than usual and are uncomfortable about this. Many females will become amenorrheic during therapy without any suppression and...

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