Do you recommend post-operative radiation therapy for gastric cancer after pre-operative chemotherapy when there is no pathologic response to chemotherapy?

Topics: Radiation Oncology • Gastrointestinal Cancers

Do factors such as large tumor size and/or node positivity affect the decision?

Answer from: Radiation Oncologist at Academic Institution

There is no level one evidence to support such a recommendation. One could argue this point either way. The counterargument is that poor response to chemotherapy predicts poor outcomes in gastroesopheal cancer and a local therapy will not change that. That is certainly the case for GEJ ACA who all g...

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