I do not routinely use anti-viral medications for HSV when treating oral lichen planus. I begin treatment with topical steroids. I would only consider testing or treating for HSV in cases of long-term recurrent and or recalcitrant disease.

When I read this question I, too, thought the poster meant HSV; however I was surprised to find that there is actually some literature on HPV in LP, specifically in the etiology of LP-associated carcinoma. However, given that the role of HPV is still not clear and that the failure to recognize a mal...