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Do you rely on HbA1c to monitor glycemic control in a patient with diabetes and compensated cirrhosis, given that advanced liver disease can systematically lower HbA1c independent of actual glucose control?

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Endocrinology · Brigham And Womens Hospital Endocrinology
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A1C is a great test, but it has many limitations. One major one is that it depends on red cell circulation time being normal for interpretation using common standards for average glucose values. Cirrhosis will potentially shorten red cell lifespan depending on associated complications and severity. ...

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