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Do you resume immunotherapy (such as nivolumab) for metastatic melanoma after therapy-induced grade 4 hyperglycemia that has resolved?

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Mednet Member
Mednet Member
Medical Oncology · UPMC Hillman Cancer Center

The answer is probably yes depending on the circumstances. If on a trial then no. If SOC then could consider it and since the patient probably has the equivalent of type 1 diabetes requiring insulin supplementation then unlikely to hurt them more. If the pancreas recovered then it would be a risk be...

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Do you resume immunotherapy (such as nivolumab) for metastatic melanoma after therapy-induced grade 4 hyperglycemia that has resolved? | Mednet