Topics:
Radiation Oncology • Sarcoma
Do you routinely boost focally positive margins after preoperative 50 Gy and surgery in patients with extremity sarcomas?
For example, a patient with liposarcoma of the lower extremity status post preoperative radiation to 50 Gy who then underwent resection and had focally positive margins close to sciatic/popliteal nerve. If you do boost, what is the maximum waiting time after surgery to allow for healing that external beam radiation boost would still be appropriate or still considered efficacious?
Answer from: Radiation Oncologist at Community Practice
Even though it was done in the Canadian randomized study comparing pre operative vs. post operative RT, retrospective data suggest hows no additional benefit with this intervention. This is likely because dose of 16 Gy would not be sufficient for residual disease. Even though it is not relevant in t...
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