Do you routinely continue using TPA/Dornase for treatment of empyema, if there is accumulation of new sero-sanguinous output from the chest tube after the initial treatment?
Are there any quantitative indices (eg. volume, pleural fluid hematocrit) that would impact your decision to stop subsequent TPA/dornase treatments?
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Do you routinely continue using TPA/Dornase for treatment of empyema, if there is accumulation of new sero-sanguinous output from the chest tube after the initial treatment ?
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1 Answer
Mednet Member
Pulmonology · Prisma Health Pulmonology And Sleep Center
Answered on
In my practice, if there is an accumulation of serosanguinous output after initial treatment, further treatment with tPa/ dornase depends on several factors.
- Hct of drainage - if > 50%, will not give further dose.
- If a patient is coagulopathic or receiving anticoagulation for a medical condition af...
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