Do you routinely include sipuleucel-T as one of your lines of systemic therapy for metastatic castration resistant prostate cancer?

In select patients, I will use Sipuleucel-T as first line therapy for patient with early castrate resistant disease that are asymptomatic. Those that I use Sipuleucel-T I will observe them post therapy unless I see a rapid increase in PSA or other symptoms, then I will start AR directed therapy. Inc...