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Do you routinely obtain a chest x-ray prior to initiating anti-TNF or other biologic therapy?

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Mednet Member
Mednet Member
Rheumatology · Johns Hopkins School of Medicine

I don't routinely order a chest x-ray in patients with negative quantiferon (or other latent TB testing such as the T-spot) before starting biologics. The chest x-ray is much less specific for latent TB, particularly in the United States where TB is not endemic. Patients may have granulomas or other...

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