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Do you routinely order double-hit assessment in cutaneous DLBCL?

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Mednet Member
Mednet Member
Medical Oncology · Rutgers Cancer Institute of New Jersey

There are certainly reported cases of primary cutaneous DLBCL that harbor double-hit mutations. Guidelines do not distinguish the workup of cutaneous DLBCL from other sites, and if a skin DLBCL were to be of germinal center immunophenotype with IHC expression of myc and bcl2 and/or bcl6, FISH would ...

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Do you routinely order double-hit assessment in cutaneous DLBCL? | Mednet