Do you still recommend adjunctive corticosteroids for tuberculous meningitis in light of more recent data showing heterogeneity in clinical outcomes?
Donovan et al., PMID 40840485
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Do you still recommend adjunctive corticosteroids for tuberculous meningitis in light of more recent data showing heterogeneity in clinical outcomes?
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2 Answers
Mednet MemberInvited Expert
Infectious Disease · Perelman School of Medicine at the University of Pennsylvania
Answered on
Though there is some disagreement in study results, a number of randomized trials and one meta-analysis support the benefit of mortality when steroids are used as adjunctive therapy for tuberculous meningitis. The use of steroids continues to be the recommendation of the WHO. In most situations, the...
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Mednet Member
Infectious Disease · Central Georgia Infectious Diseases Llc
Answered on
Despite conflicting opinions, I still believe that steroids are beneficial in conjunction with TB meningitis therapy.
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