Do you stop PPI when starting patients on immunotherapy?
2
1 Answers
Mednet Member
Medical Oncology · Mary Lanning Healthcare Morrison Cancer Center/University of Nebraska Medical Center Adjunct Faculty
Proton pump inhibitors (PPI) are commonly used in cancer patients and may affect the gut microbiome by altering gut pH. The gut microbiome plays a critical role in modulating the therapeutic effects of immune checkpoint inhibitors. PPI use in patients treated with immunotherapy has been associated w...