Do you think it makes a difference to fractionate at 2 Gy versus 1.8 Gy per fraction?
Is there evidence of decreased toxicity in the lung, brain, pelvis, breast or abdomen with 1.8 Gy fractions to justify longer treatment schedules or when using concurrent chemo? On the other hand, is there evidence of decreased tumor control when using 1.8 Gy per fraction?
1 Answer
Mednet Member
Radiation Oncology · University of Texas MD Anderson Cancer Center
Answered on
This is a great question and is an example of how a single clinical decision can change practice. In the era of radiation alone the standard fractionation was 2 Gy/day. With the introduction of concurrent chemoradiation the radiation dose was decreased to 1.8 Gy/day. This 10% dose attenuation was su...
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