Do you think there is a role for belimumab in treating lupus nephritis and if so, in which patients would you considering adding it on?
Did the recently published BLISS-LN trial change your practice?
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Will you consider adding belimumab to MMF in treatment naïve lupus nephritis patients?
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2 Answers
Mednet MemberInvited Expert
Rheumatology · NIAMS
Answered on
The results from BLISS-LN showed modest efficacy as an add-on therapy to standard of care. The improvement was significant only in the non-black patients receiving mycophenolate mofetil (MMF) as standard of care. The primary endpoint was changed in the midst of the trial but still, the complete rena...
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Mednet MemberInvited Expert
Rheumatology · Beth Israel Deaconess Medical Center
Answered on
2020 will probably go down as the year where new medications for the treatment of lupus nephritis will get approved by the FDA. Not only belimumab but also voclosporin appear to be safe and result in the improvement of outcomes in lupus nephritis.
For the time being it is reasonable to use belimumab...
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