Do you time initiation of definitive radiation on PSA response to neoadjuvant ADT?  

Is there any benefit to delaying start of RT or perhaps changing to complete adrogen blockage if maximal PSA response is not achieved in 2 mo?  

What PSA metric are you using, for example, <0.3, <0.1, other?  

Do you feel PSA reponse to ADT is a surrogate for less agressive disease or does allowing a more robust PSA repsone actually result in "more" radiosensitization and potentially better outcome?



Answer from: Radiation Oncologist at Academic Institution

Answer from: Radiation Oncologist at Community Practice