Do you treat atypical carcinoid of the lung with N2 or N3 nodal involvement with definitive concurrent chemoradiation?

Topics: Radiation Oncology • Thoracic Malignancies • Medical Oncology • Neuroendocrine Tumors

Would there be any benefit to surgery in a healthy/good PS patient? There is so little data on pulmonary atypical carcinoid and radiation response.

Answer from: Medical Oncologist at Academic Institution

I agree that these are very difficult cases due to the lack of data for either radiation or chemotherapy responsiveness in bronchopulmonary NETs. When possible we try to offer surgery. For patients with resectable N2 disease, I would recommend surgery and then consider adjuvant chemotherapy for aty...

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Medical Oncologist at University of Utah
Thank you. A pneumonectomy was performed in my pat...

Answer from: Medical Oncologist at Community Practice

Intermediate-grade (atypical) bronchial carcinoid is different from NSCLC or SCLC and we shouldn't follow the same treatment algorithm. There are significant biological differences and responses to treatment between these diseases. Although atypical carcinoid with N2/N3 disease has a higher rate ...

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Medical Oncologist at University of Utah
How about Anderson Jr. et al., PMID 28760471? Doe...

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