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Do you typically recommend initial therapy with a JAK inhibitor or systemic corticosteroids in acute extensive alopecia areata?

What factors drive this decision?
1 Answer
Mednet MemberInvited Expert
Dermatology · Mount Sinai
Answered on

I typically treat acute extensive alopecia areata with a JAK inhibitor (at the highest relevant dose) rather than systemic corticosteroids, as I have found that patients tend to respond well with this approach. The JAK inhibitors work very quickly to reduce the inflammatory processes underlying alopecia areata flares, and short-term risks for JAK inhibitors on the order of a few months are very well characterized, and they are generally very well tolerated.

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